Mitochondrial genome sequencing of marine leukaemias reveals cancer contagion between clam species in the Seas of Southern Europe
Published in eLife, 2022
Recommended citation: García-Souto, D#, Bruzos, AL#; Díaz-Costas, S# et al. (2022). "Mitochondrial genome sequencing of marine leukemias reveals cancer contagion between clam species in the Seas of Southern Europe." eLife. 11:e66946. doi: 10.7554/eLife.66946 - IF(2021) = 8.713 (#equal contribution) https://doi.org/10.7554/eLife.66946
Complete Citation:
García-Souto, D.#, Bruzos, A.L.#; Díaz-Costas, S.#; Rocha, S.; Pequeño, A.; Roman-Lewis, C.; Alonso, J.; Rodriguez, R; Costas, D.; Rodriguez-Castro, J.; Villanueva, A.; Silva, L.; Valencia, J.; Annona, G.; Tarallo, A.; Ricardo, F.; Bratos Cetinic, A.; Posada, D.; Pasantes, J.J.; Tubío, J.M.C. “Mitochondrial genome sequencing of marine leukemias reveals cancer contagion between clam species in the Seas of Southern Europe.” eLife, 11:e66946 DOI: 10.7554/eLife.66946 (#equal contribution)
Previously published on Biorxiv.
IF(2021) = 8.713
About the paper:
Scope: We report a new hemic neoplasia described on clams found on the Mediterranean and Atlantic coasts of Spain with histological, cytogenetic, TEM, and flow cytometry analysis. Furthermore, the genomic study revealed that the cancer originated on the striped clams and then spread to the warty venus clams, so it is a contagion between different species. Genetic analysis suggested a recent emergence of this cancer. Therefore, the fact that cancer is so similar in Atlantic and Mediterranean clams suggests that human activity may have contributed to its spread. Impact: These findings not only shed light onto an unknown case of inter-species bivalve contagion but highlight the importance of measures to safeguard our oceans’ health. My contribution: I was involved in all the experiments and some analyses under the supervision of Dr S Díaz, it was also included as one chapter of my doctoral thesis. Personal importance: This was my first publication as first-author, in addition, we created a “video abstract” for the general.
Watch a 2-min video here to find out the main findings of this research, we also have a Spanish version here.
More information:
Visit online version: doi.org/10.7554/eLife.66946
Download PDF here
Authorship:
Position of AL Bruzos: 2 (first authorship)
Total number of authors: 20
Authors: Daniel Garcia-Souto; Alicia L Bruzos; Seila Diaz; Sara Rocha; Ana Pequeño-Valtierra; Camila F Roman-Lewis; Juana Alonso; Rosana Rodriguez; Damian Costas; Jorge Rodriguez-Castro; Antonio Villanueva; Luis Silva; Jose Maria Valencia; Giovanni Annona; Andrea Tarallo; Fernando Ricardo; Ana Bratoš Cetinić; David Posada; Juan Jose Pasantes; Jose MC Tubio
Journal information
ISSN: 2050-084X
Current Publisher: eLIFE SCIENCES PUBL LTD, SHERATON HOUSE, CASTLE PARK, CAMBRIDGE CB3 0AX, ENGLAND
Journal Impact Factor (JIF): 8.713 (2021)
WoS Research Areas: Life Sciences & Biomedicine - Other Topics
JCR Category: BIOLOGY in SCIE edition
JCR Category Rank: 8/94
JCR Category Quartile: Q1
Peer-review process:
Received: 27 January 2021
Accepted: 04 December 2021
Published: 18 January 2022