Pan-Cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
Published in Nature Genetics, 2020
Recommended citation: Rodriguez-Martin, B. et al. (2020). "Pan-Cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition." Nature Genetics. 52:306-319. https://doi.org/10.1038/s41588-019-0562-0
Alicia’s Citation:
Rodriguez-Martin, B. et al. (includes Bruzos A.L.). 2020. “Pan-Cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition”. Nature Genetics, 52:306-319. IF = 38.333 (2020).
Other citation (more authors): Rodriguez-Martin, B; Alvarez, EG; Baez-Ortega, A; Zamora, J; Supek, F; Demeulemeester, J; Santamarina, M; Ju, YS; Temes, J; Garcia-Souto, D; Detering, H; Li, Y; Rodriguez-Castro, J; Dueso-Barroso, A; Bruzos, AL; … Tubio, JMC. (2020) Pan-Cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. Nature Genetics, 52:306-319. IF = 38.333 (2020). DOI: https://doi.org/10.1038/s41588-019-0562-0
About the paper:
Here we identify a new mutational mechanism in cancer by with aberrant integration of L1 elements promote chromosomal rearrangements such as Megabase-size genomic deletions that on occasion remove tumour suppressor genes, contributing to cancer progression. I catalogued the retrotransposition events of LINE-1.
More information:
Visit online version: doi.org/10.1038/s41588-019-0562-0
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Authorship:
Position of AL Bruzos: 15
Total number of authors: 53
Journal information
ISSN: 1061-4036
eISSN: 1546-1718
Current Publisher: NATURE PORTFOLIO. HEIDELBERGER PLATZ 3, BERLIN 14197, GERMANY
Journal Impact Factor (JIF): 38.333 (2020) WoS Research Areas: Genetics & Heredity
JCR Category: Genetics & Heredity in SCIE edition
JCR Category Rank: 2/175
JCR Category Quartile: Q1
Peer-review process:
Received: 21 September 2017
Accepted: 26 November 2019
Published: 05 February 2020
Journal cover:
