Publications and Reviews

Publications (12)

Cholesterol pathway gene variants and reduced keratinocyte cholesterol support a final common druggable pathway in hyperproliferative inflammatory skin diseases

Riachi M et al (includes Bruzos AL). 2025. "Cholesterol pathway gene variants and reduced keratinocyte cholesterol support a final common druggable pathway in hyperproliferative inflammatory skin diseases." The Journal of Investigative Dermatology, In Press. doi.org/10.1016/j.jid.2025.02.157.

Novel PCR assay for the identification of two transmissible cancers in Cerastoderma edule.

Santamarina M#, Bruzos AL#* et al. (2024). "Novel PCR assay for the identification of two transmissible cancers in Cerastoderma edule." Journal of Invertebrate Pathology, 207:108232. doi: 10.1016/j.jip.2024.108232 - IF(2023) = 3.60 (#equal contribution, *corresponding author)

Somatic evolution of marine transmissible leukemias in the common cockle

Bruzos AL, et al. (2023). "Somatic evolution of marine transmissible leukemias in the common cockle, Cerastoderma edule." Nature Cancer: 4, 1575–1591. doi: https://doi.org/10.1038/s43018-023-00641-9 - JIF(2022) = 22.07 - Journal JCR Category (2022) = D1 (11/317)

Mosaic BRAF fusions are a recurrent cause of congenital melanocytic naevi targetable by MEK inhibition

Martin SB#, Polubothu S#, Bruzos AL# et al. (2023). "Mosaic BRAF fusions are a recurrent cause of congenital melanocytic naevi targetable by MEK inhibition." The Journal of Investigative Dermatology, 144(3):593-600. doi: 10.1016/j.jid.2023.06.213 - IF(2021) = 7.590 (#equal contribution)

The first high-density genetic map of common cockle reveals a major QTL controlling shell color variation

Hermida M et al (includes Bruzos AL). (2022). "The first high-density genetic map of common cockle (Cerastoderma edule) reveals a major QTL controlling shell color variation." Scientific reports. 12:16971. doi: 10.1038/s41598-022-21214-3 - IF(2021) = 4.996

Mitochondrial genome sequencing of marine leukaemias reveals cancer contagion between clam species in the Seas of Southern Europe

García-Souto, D#, Bruzos, AL#; Díaz-Costas, S# et al. (2022). "Mitochondrial genome sequencing of marine leukemias reveals cancer contagion between clam species in the Seas of Southern Europe." eLife. 11:e66946. doi: 10.7554/eLife.66946 - IF(2021) = 8.713 (#equal contribution)

Assessing the elemental fingerprints of cockle shells (Cerastoderma edule) to confirm their geographic origin from regional to international spatial scales

Ricardo, F et al (includes Bruzos AL). (2022). "Assessing the elemental fingerprints of cockle shells (Cerastoderma edule) to confirm their geographic origin from regional to international spatial scales." STOTEN. 814:152304. doi: 10.1016/j.scitotenv.2021.152304 - IF(2021) = 10.753

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

Álvarez, EG et al (includes Bruzos AL). (2021). "Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture." Nature Communications. 12:6910. doi: 10.1038/s41467-021-26805-8 - IF(2021) = 17.694

Pan-Cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Rodriguez-Martin, B et al (includes Bruzos AL). (2020). "Pan-Cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition." Nature Genetics. 52:306-319. doi: 10.1038/s41588-019-0562-0 - IF(2020) = 38.333

Pan-Cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium (includes Bruzos AL). (2020). "Pan-Cancer analysis of whole genomes." Nature. 578:82-93. doi: 10.1038/s41586-020-1969-6 - IF(2020) = 49.962

Consortia publications: as part of the PCAWG consortium, I am an author on the following articles with my name listed:

• Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Bailey, MH et al. (includes Bruzos AL in the PCAWG). (2020). “Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.” Nature Communications 11, 4748. https://doi.org/10.1038/s41467-020-18151-y
• Sex differences in oncogenic mutational processes. Li, CH et al. (includes Bruzos AL in the PCAWG). (2020). “Sex differences in oncogenic mutational processes.” Nature Communications 11, 4330. https://doi.org/10.1038/s41467-020-17359-2

Under review publications (available as preprints or request)

• Bruzos AL et al. Prevalence of hemic neoplasia in cockles and co-habiting bivalve species in the western coast of France and the southern coast of Portugal. doi: 10.1101/2025.07.30.667629 BiorXiv
• Polubothu S et al. (includes Bruzos AL) Mosaic PRKCA fusions cause a novel congenital melanocytoma syndrome associated with uveal melanoma

Book chapters (10)

• “Multiple cancer clones metastasize the Atlantic Coast of Europe.” (2021) Bruzos, AL; Díaz, S; García, D; Rocha, S; Temes, J; Zamora, J; Rodríguez-Castro, J; Posada, D; Tubío, J. In: VIII Encontro da Mocidade Investigadora: libro de resumos. 264(1):154. Servizo de Publicacións Campus Vida, ISBN: 978-84-19155-34-4.
• “WGS y cromosomas de berberechos con cáncer transmissible: efectos en la integridad del ADN.” (2019) Bruzos, AL; Díaz, S; García, D; Rodríguez-Castro, J; Tubío, J In: Rey-Méndez M., et al. Foro dos Recursos Mariños e da Acuicultura das Rías Galegas. 22: 265- 273. ISBN: 978-84-09-19360-8; legal deposit: C 2014-2016.
• “Braquiuros en berberechos: ¿parasitismo o amensalismo?” (2019) Bruzos, AL; Lafuente, S; Tubío, J; Díaz, S. In: Rey-Méndez M., Fernández Casal J, Lastres M.A., Padín X.A. (Eds.). Foro dos Recursos Mariños e da Acuicultura das Rías Galegas. 22: 257-264, ISBN: 978-84-09-19360-8; legal deposit: C 2014-2016.
• “Germinoma en berberechos Cerastoderma edule de Dinamarca: caracterización histopatológica y genética.” (2019) Díaz, S; Bruzos, A.L.; García-Souto, D; Tubío, J In: Martínez, F.J., et al. Libro de resúmenes CNA. 2019:200-201, ISBN: 978-84-09-11292-0.
• “Neoplasia diseminada en Venus verrucosa: ¿un nuevo caso de cáncer transmisible?” (2019) Díaz, S; Bruzos, A.L.; García-Souto, D; Román Lewis, C; Rodríguez-Castro, J; Tubío, J In: Martínez, F.J., et al. Libro de resúmenes CNA. 2019:198-199, ISBN: 978-84-09-11292-0.
• “Epigenetic DNA methylation study of bivalve tumors.” (2018) García, D; Bruzos, AL; Díaz, S; Santamarina, M; Zamora, J; Pasantes, J; Tubío, J In: VI International Symposium on Marine Sciences. 2018:404. Imprenta Universidade de Vigo, ISBN: 978-84-8158-788-3.
• “Molecular cytogenetic analysis of bivalve tumors.” (2018) García, D; Bruzos, AL; Díaz, S; Santamarina, M; Zamora, J; Pasantes, J; Tubío, J In: VI International Symposium on Marine Sciences. 2018:124. Imprenta Universidade de Vigo, ISBN: 978-84-8158-788-3.
• “Cockle Reference Genome: DNA isolation challenges” (2018) Bruzos, AL; García, D; Díaz, S; Zamora, J; Temes, J, Rodríguez-Castro, J; Tubío, J. In: Arias Martínez, D., Cao Labora, D., Carbajales Barcia, L. M., Moldes Diz, Y., Muñoz Menéndez, C. & Vieites Blanco, C. VI Encontro da Mocidade Investigadora: Libro de resumos Servizo de Publicacións Campus Vida, ISBN: 978-84-09-03154-2
• “Cockle reference genome: size estimation.” (2017) Bruzos, A.L.; Díaz, S; García-Souto, D; Zamora, J; Tubío, J In: Jóvenes investigadores, 47- 51, ISBN: 978-84-945079-9-1; legal deposit: S.469-2017.
• “Primeros pasos para decodificar el genoma del berberecho C edule.” (2017) Bruzos, AL; Díaz, S; García-Souto, D; Zamora, J; Tubío, J In: Rey-Méndez M., et al. Foro dos Recursos Mariños e da Acuicultura das Rías Galegas. 20: 227-237, ISBN: 978-84-09- 01474-3.

Peer-reviewing activity

My scientific expertise has led me to several invitations to take part in the peer-review system that ensures the rigorous standards of the scientific process. In particular, I have reviewed articles for the following journals:

• 1 for Science (AAAS). IF(2021)=56.9, JCR rank (2022) 2/73 (D1)
• 1 for Science Advances (AAAS). IF(2021)=13.6, JCR rank (2022) 7/73 (D1)
• 1 for Molecular Ecology (Wiley). IF(2022)=4.9, JCR rank (2022) 8/52 (Q1)
• 1 for Proceedings of the Royal Society B - Biological Sciences. IF(2022)=4.7, JCR rank (2022) 10/52 (Q1)
• 1 for Scientific Reports.

All stated reviews have been certified by Publons / Web of Science: D-7235-2018.

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